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When both vectors of decline are present, treating only one often produces incomplete results

The aim of surgery for IVD disease is to relieve the compression of neural structures, and procedures include removal of the NP (nucleotomy) through fenestration of the AF alone or combined with partial removal of the vertebral roof (laminectomy) or vertebral body (ventral decompression) [12]

[9] [5] It is given by mouth, by injection into a muscle, or as a nasal spray

Increased levels of protein oxidation markers, malondialdehyde (MDA), serum nitric oxide and related products correlate with disease severity

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